Delusional infestation ( DI ) is a rarified and freakish circumstance . patient are perfectly confident they   are infected with   life or inanimate pathogen ( believe : louse , insects , and fungi ) when , in reality , there is nothing there .

It can be debilitate and chilling , and now , it appear , more common than previously thought . A write up published inJAMA Dermatologyestimates that 27.3 people per 100,000 ( 0.027 pct ) bear from the disorder . This would   put the number of people in the US with DI at roughly 89,400 .

Reports of DI go back to 1894   when a Parisian skin doctor called Georges Thibierge document type of patients falsely conceive they hadscabies . However ,   symptom and causal agency vary wildly . bug are a unwashed culprit . patient often sound off of " crawling " and " mordacious " sensations . They might also claim pathogen are leaving marks on their skin or building nest .

More recently , there has beenMorgellons disease , which was first identified in 2001 . sufferer are convinced there are fibers embed in their skin , left there by mysterious   – possibly alien – brute that live in the consistency .

vocaliser - songwriter Joni Mitchelldescribedit as " this weird incurable disease that seems like it ’s from proscribed place … character in a variety of people of color protrude out of my skin : they can not be forensically identified as animal , veggie or mineral . Morgellons is a slow , unpredictable slayer – a terrorist disease . It will blow up one of your organs , leave you in layer for a year . "

But a two - twelvemonth , half - a - million dollar study led by the CDC foundnothing . Doctors say it is n’t real .

While DI does not physically harm people in a direct sense , elbow grease to sample and remove the pathogens can be utmost and be given to become more elaborate with time . Aside from frequent cleansing , apparel transfer , and bed qualification , patients may repair to harsh chemicals , gasoline , whitener , and ego - mutilation .

We know that people of all ages and gender can be affected , though it is more predominant among older and mediate - maturate   adult and women outnumber military man . A   tie has also been found between DI and social closing off , but until now there had been no population - based   study of DI prevalence .

Researchers used data from the Rochester Epidemiology Project ( REP ) , a collaboration of medical quickness in Wisconsin and Minnesota , to forge out exactly how many people from Olmsted Country in Minnesota had the shape . To qualify , patients had to be a resident of the county on December 31 , 2010 .

Thirty - five patient were identified , of which 13 were men and 22 were char . The meanspirited age at the time of diagnosis was 64.5 age , the majority of whom were white , though this perhaps says more of the   homogeneous   demographics of Olmsted county than it does of DI prevalence in non - clean populations . The researchers say there is not yet enough info to make judgment about the frequence of DI in more divers biotic community .

The study also did not destine whether the cases reported were elemental DI or lowly DI ( which would make it junior-grade to psychiatric disorder like schizophrenia , drug use , or conditions such as Alzheimer ’s ) .

However , the investigator say there is enough data point to suggest that DI is currently underreported .